This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Aliases：    NECTIN3; PPR3; PRR3; PVRL3; PVRR3; CDW113; NECTIN-3    

Entrez GeneID：    25945    

Swissprot ：   Q9NQS3    

WB Predicted band size：    61kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity ：   Human    

Immunogen ：   Purified recombinant fragment of human CD113 (AA: extra 282-404) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000