This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.

Aliases:    VCAM1; INCAM-100    

Entrez GeneID:   7412    

Swissprot :   P19320    

WB Predicted band size:    81.3kDa    

Host/Isotype :   Mouse IgG1    

Species Reactivity:    Human,Rat,Monkey    

Immunogen:    Purified recombinant fragment of human CD106 (AA: extra 25-183) expressed in E. Coli.    

WB    1/500 - 1/2000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000