Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al. 2002 (PubMed 11724789). Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

Aliases：    PRMT4; CARM1    

Entrez GeneID：    10498    

Swissprot ：   Q86X55    

WB Predicted band size：    65kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity ：   Human,Mouse,Rat,Rabbit,Monkey    

Immunogen ：   Purified recombinant fragment of human CARM1 expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000