This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.

Aliases ：   NIP3    

Entrez GeneID ：   664    

Swissprot ：   Q12983    

WB Predicted band size：    21.5kDa    

Host/Isotype ：   Mouse IgG2a    

Species Reactivity ：   Human    

Immunogen ：   Purified recombinant fragment of human BNIP3 (AA: 50-155) expressed in E. Coli.    

IHC    1/200 - 1/1000    

IF/ICC    1/50 - 1/250    

FCM    1/200 - 1/400    

ELISA    1/10000