The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.

Aliases:    ANON2; BULN2    

Entrez GeneID :   627    

Swissprot:    P23560    

WB Predicted band size:    27.8kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity :   Human    

Immunogen :   Purified recombinant fragment of human BDNF (AA: 19-248) expressed in E. Coli.    

WB    1/500 - 1/2000    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000