This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Aliases:    ATL1; RIT1; CTIP2; IMD49; CTIP-2; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha    

Entrez GeneID:    64919    

Swissprot:    Q9C0K0     

WB Predicted band size:    95.5kDa    

Host/Isotype :   Mouse IgG1    

Species Reactivity :   Human    

Immunogen:    Purified recombinant fragment of human BCL11B (AA: 1-150) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000