GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.

Aliases : GALGT; SPG26; GALNACT; GalNAc-T    

Entrez GeneID:  2583    

Swissprot:  Q00973     

WB Predicted band size : 58.9kDa    

Host/Isotype:  Mouse IgG1    

Species Reactivity:  Human, Mouse, Monkey    

Immunogen:  Purified recombinant fragment of human B4GALNT1 (AA: 26-225) expressed in E. Coli.    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000