The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.

Aliases :   ASP; APG5; APG5L; hAPG5; APG5-LIKE    

Entrez GeneID :  9474    

Swissprot :  Q9H1Y0     

WB Predicted band size :  32.4kDa    

Host/Isotype :  Mouse IgG2b    

Species Reactivity :  Human    

Immunogen : Purified recombinant fragment of human ATG5 (AA: 144-275) expressed in E. Coli.    

WB    1/500 - 1/2000   

IF/ICC    1/100 - 1/500    

FCM    1/200 - 1/400    

ELISA    1/10000