The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
Aliases : IBD10; WDR30; APG16L; ATG16A; ATG16L
Entrez GeneID : 55054
Swissprot : Q676U5
WB Predicted band size : 68.3kDa
Host/Isotype : Mouse IgG1
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human ATG16L1 (AA: 11-257) expressed in E. Coli.
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