Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).

Aliases    APG10; APG10L; pp12616    

Entrez GeneID    83734    

Swissprot    Q9H0Y0    

WB Predicted band size    25.3kDa    

Host/Isotype    Mouse IgG1    

Species Reactivity    Human    

Immunogen    Purified recombinant fragment of human ATG10 (AA: 1-125) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000