The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.

Aliases:  TIC; JAP3; MOP3; BMAL1; PASD3; BMAL1c; bHLHe5; MGC47515; ARNTL    

Entrez GeneID:   406    

Swissprot:  O00327       

WB Predicted band size :   68.7kDa    

Host/Isotype :  Mouse IgG1    

Species Reactivity:   Human    

Immunogen:   Purified recombinant fragment of human ARNTL expressed in E. Coli.    

ELISA    1/10000