The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
Aliases PP4; ANX5; ENX2; RPRGL3; HEL-S-7
Entrez GeneID 308
Swissprot P08758
WB Predicted band size 36kDa
Host/Isotype Mouse IgG1
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of human ANXA5 (AA: 160-320) expressed in E. Coli.
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