Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Aliases : HIST3H3;H3t; H3.4; H3/g; H3FT
Entrez GeneID: 8290
Swissprot : Q16695
WB Predicted band size: 15.5kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human,Mouse
Immunogen : Synthesized peptide of human HH3 (AA: ARTKQTAR(AcK)STG-C).
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