This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

Aliases    DSH; AGS6; G1P1; IFI4; P136; ADAR1; DRADA; DSRAD; IFI-4; K88DSRBP    

Entrez GeneID    103    

Swissprot    P55265      

WB Predicted band size    136kDa    

Host/Isotype    Mouse IgG1    

Species Reactivity    Human    

Immunogen    Purified recombinant fragment of human ADAR (AA: 1085-1223) expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000