The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene.
Aliases ARP3
Entrez GeneID 10096
Swissprot P61158
WB Predicted band size 47.4kDa
Host/Isotype Mouse IgG1
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of human ACTR3 (AA: 287-418) expressed in E. Coli.