This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Aliases:   MCAD; ACAD1; MCADH    

Entrez GeneID:    34    

Swissprot:   P11310       

WB Predicted band size:    46.6KDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity:   Human    

Immunogen:   Purified recombinant fragment of human ACADM (AA: 26-185) expressed in E. Coli.    

IHC    1/200 - 1/1000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000