AAT, also known as SERPINA1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.
Aliases: PI; A1A; AAT; PI1; A1AT; SERPINA1
Entrez GeneID: 5265
WB Predicted band size : 47kDa
Host/Isotype: Mouse IgG1
Species Reactivity : Human,Mouse
Immunogen: Purified recombinant fragment of human AAT expressed in E. Coli.