Botulinum Toxin Type A (also known as OnabotulinumtoxinA or BoNT/A) is a potent neurotoxin produced by Clostridium botulinum. After purification, it is widely utilized in medical and aesthetic fields and stands as the most clinically prevalent type of botulinum toxin.
BoNT/A is the most toxic yet clinically mature subtype among all botulinum serotypes. It appears as a white, loose lyophilized powder that dissolves into a clear, colorless solution. Its mechanism of action involves inhibiting the release of acetylcholine at peripheral motor nerve terminals, inducing chemical denervation and flaccid paralysis. This effectively alleviates abnormal muscle contractions and improves dynamic wrinkles. In China, it is strictly classified as a toxic pharmaceutical and is restricted for dispensing and use exclusively within medical institutions.
AccuSift offers high-performance Anti-Botulinum Toxin Type A Antibody Pairs, optimized for IVD kit development (including Lateral Flow Assays, Chemiluminescence, ELISA, and POCT). Featuring high affinity, high specificity, and excellent batch-to-batch consistency, these pairs enable rapid and reliable detection.
Sensitivity: ELISA LOD: 2 ppb
Source: Mouse Monoclonal
Purity: ≥ 90%
Recommended Pair: (Coating) / (Labeling)
Storage & Shipping: Long-term storage at ≤ -20°C; short-term storage at 2-8°C. Shipped with ice packs.