The impact and effect on IVD reagents 

Polodacrilin mainly exerts emulsifying, dispersing and stabilizing effects in IVD reagents. The specific effects are as follows: 

Improving repeatability: In enzymatic test reagents, the addition of polydacrylamide can significantly reduce the coefficient of variation (CV) of the test results, making the test results more stable and reliable. 

Maintaining stability: Polodacron has excellent acid resistance, alkali resistance and hardness water resistance. In a light-protected environment at 2°C to 8°C, the reagent containing Polidocanol can be effectively stored for more than 15 months without affecting its accuracy. 

Reduce interference: In ultraviolet spectroscopy detection, when polydacrylate is combined with certain cationic surfactants (such as TDBAC), it may enhance the absorbance or form micelles that interfere with the detection. However, by adding substances such as β-cyclodextrin (β-CD), this interference can be eliminated, thereby improving the detection accuracy. 

Usage Notes 

Solubility: Polodakuril has poor solubility at room temperature. It usually needs to be dissolved in water slightly above room temperature (such as 30-40°C), or it can be first dissolved in a small amount of organic solvent (such as ethanol) and then added to the aqueous phase. 

Cloud point: The aqueous solution of polydodecanol will undergo phase separation when the temperature rises to the cloud point (approximately 70-80°C). Therefore, during the storage and transportation of the reagent, attention should be paid to the environmental temperature to avoid the reagent from stratifying due to high temperature.