AccuSift provides a high-performance S-adenosylmethionine (SAM/SAM-e) competitive assay antibody pair, characterized by exceptional batch-to-batch consistency and optimized for IVD kit development (lateral flow, chemiluminescence, ELISA, POCT). The pair offers high affinity and specificity, enabling rapid detection.

S-Adenosylmethionine (SAM/SAM-e) is a key metabolite of methionine in living organisms. As the primary intracellular methyl donor, it participates in the methylation of DNA, RNA, and proteins, maintaining methyl metabolism balance. In tumor pathology, SAM influences tumorigenesis, progression, and metastasis by regulating epigenetic states, sustaining polyamine synthesis, and mediating immune evasion. Its synthesis requires folate and vitamin B12, and SAM deficiency is commonly associated with conditions such as liver disease, coronary artery disease, and depression.

Key Performance Specifications:

• Sensitivity: ELISA IC50: 2 ppb

• Source: Mouse monoclonal antibody / synthetic BSA-conjugated antigen

• Purity: ≥ 90%

• Storage: Long-term storage at ≤ -20°C; short-term storage at 2-8°C. Shipped with ice packs.