AccuSift provides high‑performance valproic acid competitive assay pairings, characterized by exceptional batch‑to‑batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity, facilitating rapid detection.Valproic acid (VPA) is a broad‑spectrum antiepileptic drug effective for various types of epilepsy, including absence seizures, myoclonic epilepsy, focal seizures, generalized tonic‑clonic seizures, and mixed seizures. It is also used to treat manic episodes associated with bipolar disorder. Valproic acid has a narrow therapeutic range (50–100 μg/mL), and inter‑individual pharmacokinetic variability is high, resulting in poor correlation between dose and plasma concentration, large fluctuations in blood levels, and difficulty in dose adjustment. When conventional dosing is used, about half of patients have plasma concentrations outside the safe range. These factors contribute to a high incidence of adverse effects during clinical use, making therapeutic drug monitoring (TDM) essential.Performance Characteristics:
Sensitivity: ELISA IC50: 200 ppb
Source: Mouse Monoclonal Antibody
Recommended Pairing: (Coating) / (Labeling)
Storage: Long‑term storage at ≤ –20°C; short‑term storage at 2–8°C. Shipped on ice packs.
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