AccuSift provides high‑performance sirolimus competitive assay pairings, characterized by exceptional batch‑to‑batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity, facilitating rapid detection.Sirolimus is an immunosuppressive agent primarily used to prevent graft rejection after organ transplantation. It exerts its effects by modulating T‑cell activation and proliferation.Sirolimus selectively blocks mammalian target of rapamycin (mTOR) activity, thereby inhibiting T‑cell‑mediated immune responses. The drug interferes with key signaling molecules in pathways such as the phosphatidylinositol 3‑kinase/Akt pathway, reducing T‑cell activation and proliferation. Sirolimus is used to treat a variety of immune‑related conditions, such as acute rejection after kidney transplantation. The use of sirolimus may improve renal function and alleviate symptoms such as oliguria and edema.Performance Characteristics:
Sensitivity: ELISA IC50: 3 ppb
Source: Mouse Monoclonal Antibody
Recommended Pairing: (Coating) / (Labeling)
Storage: Long‑term storage at ≤ –20°C; short‑term storage at 2–8°C. Shipped on ice packs.
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