AccuSift provides high-performance competitive immunoassay antibody pairs for Metformin with exceptional lot-to-lot consistency. Optimized for IVD kit development (Lateral Flow, CLIA, ELISA, POCT), these antibodies offer high affinity and specificity to facilitate rapid detection.
Metformin is a first-line medication for the treatment of type 2 diabetes, especially in overweight patients.In 2019, a study published in Cancer Cellreported that using metformin under fasting conditions significantly inhibits tumor growth, proposing that the PP2A-GSK3β-MCL-1 pathway may be a novel target for cancer therapy. Research has shown that tumor cells exhibit metabolic alterations distinct from normal cells and can adapt to changes in the metabolic environment by switching between glycolysis and oxidative phosphorylation (OXPHOS).
Sensitivity: ELISA IC₅₀ ≈ 1 ppb
Source: Mouse Monoclonal Antibody
Recommended Pairing: (Coating) / (Label)
Storage: Store at ≤ -20°C for long-term stability. Short-term storage at 2-8°C is acceptable. Shipped on ice packs.
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