AccuSift High-Performance Medroxyprogesterone Competitive Assay PairAccuSift provides high-performance Medroxyprogesterone competitive assay pairs with exceptional lot-to-lot consistency, specifically optimized for the development of IVD kits (Lateral Flow, Chemiluminescence, ELISA, POCT). Featuring high affinity and specificity, they facilitate rapid detection.Medroxyprogesterone is a medication used for gonadal disorders. It is a potent progestin with no estrogenic activity. Its primary functions include promoting endometrial proliferation and secretion to prepare for conception and supporting fetal development. It also alters the menstrual cycle, increases cervical mucus viscosity, and inhibits ovulation. At high doses, Medroxyprogesterone exhibits antitumor effects, significantly improves appetite, and alleviates pain. It counteracts the effects of estrogen while preserving estrogen's beneficial impact on lipoproteins and shows minimal androgenic activity, closely resembling natural progesterone. It primarily increases cervical mucus viscosity; high doses suppress pituitary gonadotropins to inhibit ovulation, providing long-acting contraceptive effects. As an antitumor hormone, extensive experimental and clinical studies have demonstrated that this agent has dual, dose-dependent mechanisms of action.Sensitivity: ELISA IC50: 0.07 ppb; Colloidal Gold: 50 ppb
Cross-reactivity: 17α-Hydroxyprogesterone (17-α-OH-P): 1 ppbSource: Mouse Monoclonal AntibodiesRecommended Pairing: (Coating) / (Labeling)Storage: For long-term storage, keep at ≤ -20°C; for short-term storage, keep at 2-8°C. Shipped with ice packs.
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