AccuSift provides high-performance TYL/TIM/TYV competitive assay pairings, characterized by exceptional batch-to-batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity, facilitating rapid detection.•Tylosin (TYL): A broad-spectrum antibiotic particularly effective against Mycoplasma. It exhibits strong antibacterial activity against various Gram-positive bacteria (G+) and also inhibits certain Gram-negative bacteria (G-), Campylobacter, spirochetes, and coccidia.
•Tilmicosin (TIM): An over-the-counter veterinary antibiotic, semi-synthesized from a hydrolysis product of tylosin and specifically used for livestock and poultry. Its drug form is the phosphate salt. It inhibits Gram-positive bacteria, certain Gram-negative bacteria, mycoplasma, and spirochetes. Tilmicosin demonstrates stronger antibacterial activity against Actinobacillus pleuropneumoniaeand Pasteurellacompared to tylosin.
•Tylvalosin (TYV, Aivlosin): A macrolide antibiotic primarily used in animal husbandry, showing prominent efficacy particularly in swine disease prevention and control. Compared to tylosin, it achieves higher blood concentration (up to 3 times) and is lipophilic, allowing it to enter cells and exert antiviral effects. Key target diseases include swine enzootic pneumonia (Mycoplasma), PRRS (inhibiting viral replication), and porcine ileitis. Tylvalosin's efficacy against Mycoplasma and ability to inhibit PRRS virus are significantly superior to tiamulin.
Performance Characteristics:
•Sensitivity: ELISA IC50: 0.6 ppb; Colloidal Gold Visual Cut-off: 10 ppb
•Cross-Reactivity: Tilmicosin 2.4 ppb, Tacrolimus 1 ppb, Decontamination tylosin 0.6 ppb, Tylvalosin 2 ppb
•Source: Mouse Monoclonal Antibody
•Purity: ≥ 90%
•Recommended Pairing: (Coating) / (Labeling)
•Storage: Long-term storage at ≤ -20°C; short-term storage at 2-8°C. Shipped on ice packs.
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