AccuSift provides high-performance Clindamycin competitive assay pairings, characterized by exceptional batch-to-batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity, facilitating rapid detection.Clindamycin is an antibiotic with activity against Gram-positive bacteria and anaerobic organisms. It is used to treat abdominal and gynecological infections, Staphylococcus aureus osteomyelitis, as well as respiratory tract and skin/soft tissue infections. Common adverse effects include gastrointestinal reactions such as nausea and diarrhea; severe cases may involve pseudomembranous colitis, anaphylactic shock, or acute kidney injury. The injectable form can cause hematuria and renal impairment, and may induce systemic effects like laryngeal edema, dyspnea, and allergic purpura. It should be used with caution in pregnant or breastfeeding women and children, and is contraindicated in individuals with a history of lincosamide allergy. Clinical use requires strict adherence to dosing guidelines. Concomitant use with aminoglycoside antibiotics should be avoided to prevent enhanced neuromuscular blockade, and intravenous infusion concentration and rate must be controlled. The National Medical Products Administration has updated its prescribing information to include warnings regarding risks of liver and kidney injury.Performance Characteristics:
•Sensitivity: ELISA IC50: 0.5 ppb
•Cross-Reactivity: Lincomycin 5 ppb, Pirlimycin 20 ppb
•Source: Mouse Monoclonal Antibody
•Purity: ≥ 90%
•Recommended Pairing: (Coating) / (Labeling)
•Storage: Long-term storage at ≤ -20°C; short-term storage at 2-8°C. Shipped on ice packs.
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