The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. Female mice lacking this gene do not form a stable zona matrix and are sterile. Alternative splicing results in multiple transcript variants.
Aliases: ZPA; Zp-2; OOMD6
Entrez GeneID: 7783
Swissprot : Q05996
WB Predicted band size: 82.3kDa
Host/Isotype: Mouse IgG1
Antibody Type Primary antibody
Species Reactivity : Human, Mouse, Rat
Immunogen: Purified recombinant fragment of human ZP2 (AA: 624-745) expressed in E. Coli.