This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.
Aliases: BZP; TCF8; AREB6; FECD6; NIL2A; PPCD3; ZFHEP; ZFHX1A; DELTAEF1
Entrez GeneID: 6935
Swissprot: P37275
WB Predicted band size: 124kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human ZEB1 (AA: 967-1108) expressed in E. Coli.