This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
Aliases： 1C5; HS1; 14-3-3
Entrez GeneID： 10971
Swissprot： P27348
WB Predicted band size： 27.8kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human,Mouse,Rat,Monkey
Immunogen： Purified recombinant fragment of human YWHAQ (AA: 1-245) expressed in E. Coli.
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