This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.

Aliases：    ALFY; BCHS; MCPH18; ZFYVE25    

Entrez GeneID：    23001    

Swissprot :   Q8IZQ1     

WB Predicted band size：    395kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity ：   Human    

Immunogen：    Purified recombinant fragment of human WDFY3 (AA: 3277-3526) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000