This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients.
Aliases: p97; TERA; CDC48; FTDALS6
Entrez GeneID: 7415
Swissprot : P55072
WB Predicted band size: 89.3kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human, Mouse
Immunogen: Purified recombinant fragment of human VCP (AA:707-806) expressed in Mammalian system