The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Aliases：    N2DL-1; RAET1I; NKG2DL1    

Entrez GeneID：    80329    

Swissprot :   Q9BZM6    

WB Predicted band size：    28kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human ULBP1 (AA: 26-216) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000