The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.

Aliases:    BYK; Dtk; RSE; Rek; Sky; Tif; Etk-2    

Entrez GeneID:    7301    

Swissprot :   Q06418    

WB Predicted band size:    96.9kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity:    Human    

Immunogen:    Purified recombinant fragment of human TYRO3 (AA: extra 230-429) expressed in mammalian.    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000