Tubulin, beta 3, also known as TUBB3. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non exchangeable site on the alpha-chain. Tubulin is a highly conserved protein with a molecular weight of ~50 kD. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. The two main tubulin isoforms, a- and

Aliases:    tubulin, beta 3; MC1R; TUBB4    

Entrez GeneID:    10381    

Swissprot :   Q13509    

WB Predicted band size:    50~55kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity:    Human,Mouse,Rat    

Immunogen:    Purified recombinant fragment of human TUBB3 expressed in E. Coli.    

WB    1/500-1/2000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000