The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Aliases:    CMH2; RCM3; TnTC; cTnT; CMPD2; LVNC6    

Entrez GeneID:    7139    

Swissprot ：   P45379    

WB Predicted band size:    36kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity:    Human    

Immunogen:    Purified recombinant fragment of human troponin T2 expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000