The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis.

Aliases:    DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4    

Entrez GeneID:    8793    

Swissprot:    Q9UBN6    

WB Predicted band size:    41.8kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity:    Human,Mouse    

Immunogen:    Purified recombinant fragment of human TNFRSF10D (AA: extra 56-211) expressed in E. Coli.    

WB    1/500 - 1/2000    

ELISA    1/10000