Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternate splicing results in multiple transcript variants of this gene.
Aliases: ML; TPO; MGDF; MKCSF; MPLLG
Entrez GeneID: 7066
Swissprot: P40225
WB Predicted band size: 37.8kDa
Host/Isotype: Mouse IgG2a
Species Reactivity : Human
Immunogen: Purified recombinant fragment of human THPO expressed in E. Coli.