The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
Aliases: TSP; THBS; TSP1; TSP-1; THBS-1
Entrez GeneID: 7057
Swissprot : P07996
WB Predicted band size: 129kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human THBS1 (AA: 750-850) expressed in E. Coli.