This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Aliases：    BGCAN; betaglycan    

Entrez GeneID：    7049    

Swissprot：    Q03167    

WB Predicted band size：    93.4kDa    

Host/Isotype：    Mouse IgG2b    

Species Reactivity：    Human,Mouse    

Immunogen：    Purified recombinant fragment of human TGFBR3 (AA: 147-328 ) expressed in E. Coli.    

WB    1/500-1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000