The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.

Aliases：    AP-2; BOFS; AP2TF; TFAP2; AP-2alpha    

Entrez GeneID：    7020    

Swissprot：    P05549       

WB Predicted band size：    48kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human,Mouse,Monkey,Rat    

Immunogen：    Purified recombinant fragment of human TFAP2A (AA: 1-100) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000