This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

Aliases：    TRF2; TRBF2    

Entrez GeneID：    7014    

Swissprot：    Q15554    

WB Predicted band size：    55.6kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. Coli.    

IHC    1/200 - 1/1000    

ELISA    1/10000