Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.

Aliases：    E2A; ITF1; VDIR; bHLHb21; MGC129647; MGC129648; TCF3    

Entrez GeneID：    6929    

Swissprot：    P15923    

WB Predicted band size：    67.6kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human TCF3 expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000