The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Aliases:    CMD1; SRA1; CMPD1    

Entrez GeneID:    6662    

Swissprot:    P48436    

WB Predicted band size:    56kDa    

Host/Isotype:    Mouse IgG1       

Species Reactivity:    Human    

Immunogen:    Purified recombinant fragment of human SOX9 expressed in E. Coli.    

WB    1/500 - 1/2000    

IF/ICC    1/200 - 1/1000    

ELISA    1/10000