Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by this gene localizes to the capsule associated with the mitochondrial outer membranes and is thought to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath.
Aliases: MCS; MCSP; HSMCSGEN1
Entrez GeneID: 4184
Swissprot: P49901
WB Predicted band size: 12.8kDa
Host/Isotype: Mouse IgG2b
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human SMCP (AA: FULL(1-116)) expressed in E. Coli.