This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Aliases：    EEN; CNSA1; SH3P8; SH3D2B    

Entrez GeneID：    6455    

Swissprot：   Q99961 

WB Predicted band size：    41.5kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human SH3GL1 (AA: 12-119) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000