This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
Aliases: ESET; KG1T; KMT1E; KIAA0067; H3-K9-HMTase4; SETDB1
Entrez GeneID: 9869
Swissprot : Q15047
WB Predicted band size: 180kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human,Mouse,Monkey
Immunogen : Purified recombinant fragment of human SETDB1 expressed in E. Coli.