This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Aliases：    PAI; PAI1; PAI-1; PLANH1    

Entrez GeneI：D    5054    

Swissprot：    P05121    

WB Predicted band size：    45kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human,Mouse,Rat,Rabbit    

Immunogen：    Purified recombinant fragment of human SERPINE1 expressed in E. Coli.    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000