This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Aliases：    FP; PGL5; SDH1; SDH2; SDHF; CMD1GG; MC2DN1; NDAXOA    

Entrez GeneID：    6389    

Swissprot：    P31040    

WB Predicted band size：    72.7KDa    

Host/Isotype：    Mouse IgG2a    

Species Reactivity：   Human, Mouse    

Immunogen：    Purified recombinant fragment of human SDHA (AA: 516-665) expressed in E. Coli.  

WB    1/500 - 1/2000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000