Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.Tissue specificity: Mammary gland specific. Over-expressed in breast cancer.
Aliases： MGB1; UGB2; MGC71974; SCGB2A2
Entrez GeneID： 4250
Swissprot： Q13296
WB Predicted band size： 11kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human SCGB2A2 expressed in E. Coli.
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