This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.

Aliases：    AML2; CBFA3; PEBP2aC    

Entrez GeneID：    864    

Swissprot：    Q13761    

WB Predicted band size：    44.4kDa    

Host/Isotype：    Mouse IgG2b    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human RUNX3 (AA: 294-429) expressed in E. Coli.    

IHC    1/200 - 1/1000    

IF/ICC    1/50 - 1/250    

FCM    1/200 - 1/400    

ELISA    1/10000